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Study Finds Marijuana Use May Damage Women’s Eggs, Raising Infertility Risks

Scientific study links marijuana’s THC to egg cell damage, infertility, miscarriage risk, and potential genetic defects.

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A recent study published in Nature Communications warns that marijuana use may damage oocytes, the unfertilised eggs in female ovaries, potentially leading to infertility, miscarriage, and genetic defects in babies.

Elevated levels of tetrahydrocannabinol (THC), marijuana’s psychoactive ingredient, were linked to disrupted egg maturation and increased chromosome malformations. With cannabis use during pregnancy rising sharply, these new findings add to concerns over adverse pregnancy outcomes such as autism, low birth weight, premature births, and infant mortality.

THC’s Effects on Oocyte Quality and Fertility

The study analysed ovarian fluid from over 1,000 individuals undergoing infertility treatments, noting that those with detectable THC had higher oocyte maturation rates but fewer embryos with correct chromosomal counts. Dr Cynthia Duval, lead researcher, cautioned that while rapid maturation might appear beneficial, it could actually reduce egg quality by not allowing chromosomes enough time to align properly for healthy fertilisation.

“This is a hypothesis,” she said, urging further research before broad conclusions. Dr Jamie Lo, obstetrician at Oregon Health & Science University, emphasised the need for caution among women planning to conceive, especially given the rising THC exposure.

Rising Cannabis Use Among Pregnant Women and Associated Risks

Self-reported cannabis use among pregnant women in the US has more than tripled since 2002. Multiple studies have associated prenatal marijuana exposure with serious fetal and neonatal risks, including poor growth, autism, prematurity, and death.

Research by the National Institutes of Health also suggests that cannabis use may reduce conception chances by disrupting hormone levels essential for ovulation and embryo implantation. Experts urge women trying to conceive or who are pregnant to avoid cannabis use until more definitive evidence is available.

Expert Advice on Cannabis and Fertility

Health experts emphasise that cannabis contains THC, which disrupts ovulation cycles, reduces luteinizing hormone responsible for egg production, and increases miscarriage risks. The American Society for Reproductive Medicine recommends women trying to conceive or undergoing fertility treatments abstain from marijuana use.

Prolonged use can lead to anovulation, when no egg is released, making pregnancy impossible, and may also impair embryo implantation and increase miscarriage rates. Women should seek medical guidance about any cannabis use when planning pregnancy.

The Logical Indian’s Perspective

As marijuana use becomes increasingly accepted, The Logical Indian stresses the importance of informed decisions grounded in scientific evidence regarding reproductive health. Awareness about potential risks to fertility and fetal development should be raised compassionately, without stigma, empowering individuals with knowledge to safeguard maternal and child wellbeing.

This growing body of research calls for stronger public education and healthcare guidance to ensure safer pregnancies and healthier future generations. 

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