London Patient Free Of AIDS Virus After Transplant, Doctors Cautioned Too Early To Say He Is Cured

The Logical Indian Crew

March 5th, 2019 / 3:07 PM

Image Credit: MadameNoire – iOne Digitalytimg.com

 

A man in Britain has become the second person to be cleared of the HIV after he received a bone marrow transplant from an HIV-resistant donor, reported The Guardian. He had received the bone marrow stem cells from a donor three years ago with a rare genetic mutation that resists HIV infection. A British study published on March 5 in the science journal Nature said that after 18 months of quitting antiretroviral drugs, a highly sensitive test shows that the man has no trace of his previous HIV infection.

Ravindra Gupta, a professor and HIV biologist who co-led the team of doctors treating the man said, “There is no virus there that we can measure. We can’t detect anything”. He also said that his patient is “functionally cured” and “in remission”. He further added that it is too early to say that he is cured.

The patient is being called “the London patient” because his case is similar to the first known case of a functional cure of HIV. The first person, an American citizen, Timothy Brown was called “the Berlin Patient” as he underwent his treatment in Germany in 2007. He also received a bone marrow transplant of stem cells from a donor with two copies of the mutation of the gene CCR5. As of now, he is still HIV-free.


Last chance

Gupta who is now at Cambridge University, treated the London patient when he was working at University College London. The man had contracted HIV in 2003 and was also diagnosed with a type of blood cancer called Hodgkin’s lymphoma. In 2016, when he was ill with cancer, doctors as the last chance of survival decided to find a transplant match for him. They found a donor who was unrelated and had a genetic mutation known as CCR5 delta 32. This genetic mutation resists HIV. Gupta said that the transplant procedure was smooth. However, the patient suffered a period of “graft-versus-host” disease in which donor immune cells attack the recipient’s immune cells.

Most experts say that the treatment used in case of “the London patient” and “the Berlin patient” is risky, complicated and expensive. To find exact match donor in the tiny proportion is a difficult task. The experts are yet to understand that whether the CCR5 resistance is the actual reason that is curing the HIV aids virus or is it the graft-versus-host disease. Gupta said that the team had planned to use the recent findings to explore potential HIV treatment strategies.


The Logical Indian Take

Though the world has witnessed some critical advancement in the medical sector, certain diseases are still worrying the doctors and patients. One such disease is HIV-AIDS, which is a complex disease that has killed 35 million people worldwide since it began in the 1980s. Doctors have come up with various drug combinations that can keep it at bay in most patients. This new treatment, though a risky one is a new ray of hope for a large number of people. We hope that this treatment help more and more people to get cured of this fatal disease.

Also Read: Delhi HC Asks AAP Govt To Increase Assistance To Aids Patients, Slams Them For Free Electricity And Water Scheme


Contributors

Written by : Debarghya Sil

Edited by : Bharat Nayak

Related Stories

AMU Sedition

Republic TV, AMU Clash: Police Say Early Probe Suggests No Evidence To Support Sedition Charges Against Students

Too Scared To Trust Humans, Say Pet Lovers About Puppy Who Survived The Cruelty In Kolkata

Liver Cirrhosis

“While Waiting For An External Donor, We Got Tested & I Was A Perfect Match For The Transplant”

First In The World: Baby Born Via Womb Transplant From A Deceased Donor In Brazil

Chennai: Foreign Patient Preferred Over Indian Patients For Organ Transplants, Says Reports

Organ Transplant Racket: Organs Given To Foreigners Bypassing Indian Patients On The Waiting List In Chennai

Kerala Fights: In Just Five Weeks Nipah Virus Completely Wiped From The State, Last Two Patients Successfully Cured

Latest on The Logical Indian

Exclusive

‘Give Us Any Small Space In This City To Feed The Poor’: Hyderabad Man Who Feeds 400 People Daily

News

Five Men Made To Enter 14-Foot-Deep Manhole For UP Govt’s Jal Nigam Work, Lose Their Lives

News

“A Political Giant, Lost A Valued Friend” PM On Arun Jaitley’s Demise; Condolences Pour In

News

Government’s Measures To Boost Economy: The Most Important Highlights From Finance Minister’s Speech

News

FATF Puts Pakistan On ‘Enhanced Blacklist’ After Failing To Curb Terror Financing

News

To Revive India’s Economy, Finance Minister Announces Cheaper Loan, Relief For Investors

x

Stories that deserve attention, delivered to your inbox!

Handpicked, newsworthy stories which deserve the attention of a rational generation.